There is exciting new research that was released recently by Dr. Shaw at Great Plains Laboratory. This research suggests that a human enzyme is elevated in individuals that have contracted COVID19. This enzyme is phospholipase A2 (PLA2) and is also elevated in inflammatory conditions that include MS, RA, cancer and seizure disorders. Phospholipase A2 is an enzyme (catalyst) that is present in human tissue. When an infection is present, PLA2 activates a cascade that results in the widespread cell and tissue damage. It’s critical to identify if your PLA2 levels are elevated, and/or are taking the best nutritional interventions to ensure that the PLA2 remains at a normal level.
The research by Great Plains Laboratory supports the literature of MS, RA and cancer as associated with elevated levels of PLA2. . Through research on my own, I’ve identified several researched articles that suggest that elevated PLA2 is elevated in those with seizure disorders. This research is extremely important because it reinforces the vulnerability of those individuals that are having seizures but also provides important interventions and even a testing methodology.
The research that concludes elevated PLA2 and seizure disorders go hand in hand.
Neurological disorders, such as ischemia, spinal cord injury, Alzheimer’s disease, multiple sclerosis, prion diseases, and epilepsy are characterized by inflammatory reactions, oxidative stress, altered phospholipid metabolism, accumulation of lipid peroxides, and increased phospholipase A2 activity. Increased activities of phospholipases A2 and generation of lipid mediators may be involved in oxidative stress and neuroinflammation associated with the above neurological disorders.
The research comes forth at an excellent time to further support the optimal function of this enzyme. Testing is available through Great Plains Laboratory. As a qualified practitioner I can order this lab test and ship to your home. The cash price is $179 and can be ordered through this link. In addition, there are certain supplementation that may be (I emphasize may be) inflammatory to the PLA2 enzyme. One of these supplements is phosphatidyl choline. In my practice, I have recommended it to clients, where we suspect or have found through testing the presence of mycotoxins (mold). However, if (again I emphasize “if”) there is an elevation in PLA2 enzyme, phosphatidyl choline may be worsening the inflammation of this enzyme. If, you or your loved one saw improvements with the support of phosphatidyl choline, please continue the supplementation. However, if phosphatidyl choline is problematic for certain individuals, this may be explained with an elevated PLA2. Of course, PLA2 can be tested through an at-home urine sample kit as mentioned above.
What can be an inhibitor of PLA2? Cytidine 5-diphospho-choline (CDP-choline) is a precursor in the formation of phospholipids (fats that support cell membranes) is the best proposed inhibitor of PLA2 and the recommended method for reducing inflammation in this enzyme. If you are interested in ordering this product, New Beginnings is offering a 25% discount code until April 30th, 2020 (CDP25%) and you can find their link here.
Dr. Shaw also suggested as well that EPA/DHA from fish oil may also help in reducing PLA2.
Bringing much light
Lynn
